Establish an internationally recognized phronesis medicine paradigm driven by proteomics technology, promoting the realization of phronesis medicine modes based on "prediction, prejudge, prewarn, and prevention." Create demonstration pipelines for "four-pre" phronesis medicine targeting major chronic diseases, tumors, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, and infectious epidemics caused by pathogenic microorganisms. Facilitate the transformation of personalized diagnosis and treatment fields based on life omics technology from a follower to a leader role, by promoting the transition from genomics-driven precision medicine to proteomics-driven phronesis medicine paradigms.