Ruedi Aebersold

Ruedi Aebersold is a prominent proteomic scientist currently affiliated with the Institute of Molecular Systems Biology at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. He is a professor of Systems Biology and also serves as a faculty member at the University of Washington's Department of Genome Sciences in Seattle, USA. Throughout his illustrious career, Aebersold has made significant contributions to the field of proteomics, the large-scale study of proteins and their functions. One of Aebersold's major research achievements is the development of the Isotope-Coded Affinity Tag (ICAT) method, which revolutionized quantitative proteomics by allowing researchers to accurately measure and compare protein levels in different samples. He also played a pivotal role in creating the Molecular Systems Biology journal, which has become an influential publication within the field. In addition to ICAT, Aebersold has contributed to the development of several other groundbreaking proteomic technologies, such as Selected Reaction Monitoring (SRM) and Data-Independent Acquisition (DIA). These innovations have significantly advanced our understanding of complex biological systems and facilitated the discovery of novel diagnostic and therapeutic targets for various diseases. Aebersold's outstanding work has earned him numerous awards and recognitions, including the prestigious Karger Medal in 2005, the ABRF Award in 2010, and the Heinrich Wieland Prize in 2014. In 2016, he was awarded the Human Proteome Organization (HUPO) Lifetime Achievement Award in recognition of his pioneering contributions to the field of proteomics. Most recently, in 2021, he received the Benjamin Franklin Medal in Life Science from the Franklin Institute, further solidifying his status as a leading figure in the world of proteomics and systems biology.